CAPZB Antibody

Datasheet
Code CSB-PA004514ESR2HU
Size US$167Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P47756
Image
  • Western blot
    All lanes: CAPZB antibody at 6µg/ml
    Lane 1: 293T whole cell lysate
    Lane 2: A431 whole cell lysate
    Lane 3: Jurkat whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 32, 31 kDa
    Observed band size: 32, 31 kDa

  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA004514ESR2HU at dilution of 1:100

Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunogen Recombinant Human F-actin-capping protein subunit beta protein (1-272AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200
Relevance F-actin-capping proteins bind in a Ca2+-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization.
Form Liquid
Conjugate Non-conjugated
Storage Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method Antigen Affinity Purified
Isotype IgG
Clonality Polyclonal
Alias F-actin-capping protein subunit beta (CapZ beta), CAPZB
Immunogen Species Human
Research Area Signal Transduction
Target Names CAPZB
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization.
Subcellular Location Cytoplasm, cytoskeleton, Cytoplasm, myofibril, sarcomere
Protein Families F-actin-capping protein beta subunit family
Database Links

HGNC: 1491

OMIM: 601572

KEGG: hsa:832

STRING: 9606.ENSP00000264202

UniGene: Hs.432760

Pathway Endocytosis

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