CDCA7L Antibody, FITC conjugated

1. Suppression of CDCA7L limits multiple myeloma proliferation through apoptosis. PMID: 27882933
2. We identify the Myc-interacting protein JPO2 and its partner binding protein LEDGF/p75 as critical modulators of PI3K/AKT signaling and metastasis in medulloblastoma PMID: 27013196
3. common LEDGF/p75 interaction interface shared by JPO2, PogZ, MLL1, IWS1 and HIV IN PMID: 26245978
4. The data are consistent with the rs4487645-CDCA7L loci being responsible for the chromosome 7p11.2 association with multiple myeloma risk, probably exerting its effects through an extended pathway involving IRF4 and MYC. PMID: 25480495
5. Data indicate that JPO2 and LEDGF/p75 interact directly and specifically in vivo through the specific interaction domain of JPO2 and the C-terminal domain of LEDGF/p75. PMID: 24634210
6. CDCA7L was able to activate the extracellular signal-regulated kinase 1/2 (ERK1/2) signaling pathway and regulate the cell cycle, thus promoting HCC progression. PMID: 24141559
7. Reduction in R1 repressor protein correlates significantly with an increase (approximately 40%) in monoamine oxidase A protein levels within the major depressive disorder groups compared with controls. PMID: 21654740
8. monoamine oxidase A activation of glucocorticoids and androgens is regulated differently by R1 and Sp1 PMID: 16728402
9. demonstrates the functions of MAO A and its repressor R1(RAM2/CDCA7L/JPO2) in apoptotic signaling pathways PMID: 16829576
10. Over-expression of JPO2 resulted in a modest but reproducible inhibition of HIV-1 replication, consistent with competition between integrase and JPO2 for binding to LEDGF/p75 PMID: 17669426

Show More

Hide All

HGNC: 30777

OMIM: 609685

KEGG: hsa:55536

STRING: 9606.ENSP00000383986

UniGene: Hs.744069