CDKL3 Antibody

Code CSB-PA150181
Size US$297Purchase it in Cusabio online store
(only available for customers from the US)
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  • Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue, using CDKL3 antibody.
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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) CDKL3 Polyclonal antibody
Uniprot No. Q8IVW4
Target Names CDKL3
Alternative Names CDKL3 antibody; CDKL3 protein antibody; CDKL3_HUMAN antibody; Cyclin dependent kinase like 3 antibody; Cyclin-dependent kinase-like 3 antibody; Serine/threonine-protein kinase NKIAMRE antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Synthesized peptide derived from internal of Human CDKL3.
Immunogen Species Homo sapiens (Human)
Clonality Polyclonal
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration It differs from different batches. Please contact us to confirm it.
Form Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications ELISA,IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:50-1:100
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Applications : Western blot assays

Sample type: Human cells

Review: The effect of Mg2+ on the protein levels of CDKL3 in the wild-type and the mutant HeLa cells. The protein expression of CDKL3 was quantified by band intensity of the western blots with normalization to GAPDH protein. The quantified band intensity is displayed as the relative amount to the proteins in wild-type HeLa cells incubated at 0 mM Mg2+.

By Anonymous

Target Background

Gene References into Functions
  1. NKIAMRE is a member of a conserved family of kinases with homology to both MAP kinases and cyclin-dependent kinases PMID: 12927787
  2. cdkl3 transfected in anchorage-independent (suspension) HeLa cells overexpressed relative to attached cells and lead to elevated proliferation and faster transition G0/G1 phases to S phase relative to controls. Same in two HEK-293 and a CHO cell lines. PMID: 17945021
  3. data suggest that the CDKL3 gene is a strong candidate for nonsyndromal autosomal dominant mild mental retardation PMID: 18412109
Subcellular Location Cytoplasm
Protein Families Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily
Database Links

HGNC: 15483

OMIM: 608459

KEGG: hsa:51265

STRING: 9606.ENSP00000265334

UniGene: Hs.719926

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