CDKL3 Antibody

Code CSB-PA150181
Size US$297
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  • Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue, using CDKL3 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CDKL3 Polyclonal antibody
Uniprot No.
Target Names
CDKL3
Alternative Names
CDKL3 antibody; CDKL3 protein antibody; CDKL3_HUMAN antibody; Cyclin dependent kinase like 3 antibody; Cyclin-dependent kinase-like 3 antibody; Serine/threonine-protein kinase NKIAMRE antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from internal of Human CDKL3.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:50-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews
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Applications : Western blot assays

Sample type: Human cells

Review: The effect of Mg2+ on the protein levels of CDKL3 in the wild-type and the mutant HeLa cells. The protein expression of CDKL3 was quantified by band intensity of the western blots with normalization to GAPDH protein. The quantified band intensity is displayed as the relative amount to the proteins in wild-type HeLa cells incubated at 0 mM Mg2+.

By Anonymous

Target Background

Gene References into Functions
  1. NKIAMRE is a member of a conserved family of kinases with homology to both MAP kinases and cyclin-dependent kinases PMID: 12927787
  2. cdkl3 transfected in anchorage-independent (suspension) HeLa cells overexpressed relative to attached cells and lead to elevated proliferation and faster transition G0/G1 phases to S phase relative to controls. Same in two HEK-293 and a CHO cell lines. PMID: 17945021
  3. data suggest that the CDKL3 gene is a strong candidate for nonsyndromal autosomal dominant mild mental retardation PMID: 18412109
Subcellular Location
Cytoplasm.
Protein Families
Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily
Database Links

HGNC: 15483

OMIM: 608459

KEGG: hsa:51265

STRING: 9606.ENSP00000265334

UniGene: Hs.719926

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