CEP83 Antibody

Datasheet

Code	CSB-PA896730ESR2HU
Size	US$166
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Image	Western blot All lanes: CEP83 antibody at 2.27 μg/ml Lane 1: Mouse liver tissue Lane 2: COLO205 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 83, 68 kDa Observed band size: 83, 45 kDa Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA896730ESR2HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA896730ESR2HU at dilution of 1:100 Immunofluorescent analysis of PC-3 cells using CSB-PA896730ESR2HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) CEP83 Polyclonal antibody

Uniprot No.

Q9Y592

Target Names

CEP83

Alternative Names

CEP83 antibody; CCDC41Centrosomal protein of 83 kDa antibody; Cep83 antibody; Coiled-coil domain-containing protein 41 antibody; Renal carcinoma antigen NY-REN-58 antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Centrosomal protein of 83 kDa protein (34-260AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, WB, IHC, IF

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Component of the distal appendage region of the centriole involved in the initiation of primary cilium assembly. May collaborate with IFT20 in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium during the initiation of primary cilium assembly.

Gene References into Functions

We have identified mutations in CEP83, another distal appendages component encoding gene, as a cause of infantile nephronophthisis associated with central nervous system abnormalities in half of the individuals. PMID: 24882706
CCDC41 is required for the docking of ciliary vesicles PMID: 23530209

Involvement in disease

Nephronophthisis 18 (NPHP18)

Subcellular Location

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localizes specifically to the distal appendage region of the centriole, which anchors the mother centriole to the plasma membrane. Localizes to centrioles at all stages of the cell cycle, including mitosis.

Protein Families

CEP83 family

Database Links

HGNC: 17966

OMIM: 615847

KEGG: hsa:51134

STRING: 9606.ENSP00000344655

UniGene: Hs.279209

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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