CER1 Antibody

Datasheet

Code	CSB-PA005669
Size	US$100
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Image	Western Blot analysis of MCF-7 cells using Cerberus Polyclonal Antibody.
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

O95813

Target Names

CER1

Alternative Names

CER 1 antibody; cer1 antibody; CER1_HUMAN antibody; Cerberus 1 (Xenopus laevis) homolog (cysteine knot superfamily) antibody; Cerberus 1 antibody; Cerberus 1 cysteine knot superfamily homolog (Xenopus laevis) antibody; Cerberus antibody; Cerberus related 1 antibody; Cerberus related protein antibody; Cerberus-related protein antibody; Cerberus1 antibody; DAN domain family member 4 antibody; DAND 4 antibody; DAND4 antibody; MGC119894 antibody; MGC119895 antibody; MGC96951 antibody

Raised in

Rabbit

Species Reactivity

Human,Rat

Immunogen

Synthesized peptide derived from the Internal region of Human Cerberus.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

WB, ELISA

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:20000

Protocols

Western Blotting(WB) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Cytokine that may play a role in anterior neural induction and somite formation during embryogenesis in part through a BMP-inhibitory mechanism. Can regulate Nodal signaling during gastrulation as well as the formation and patterning of the primitive streak.

Gene References into Functions

Cerberus binds and inhibits Nodal, Activin B, BMP-6, and BMP-7 but not BMP-2 or Activin A. PMID: 26802359
No significant association between the studied DKK1 variations and osteoporosis was found, while CER1 variations seem to play a significant role in the determination of osteoporosis, combined with bone markers, in postmenopausal osteoporotic women. PMID: 24138842
results show that Cer1 (or CER1) serves as a good marker for quantification of definitive endoderm differentiation of mouse and human ES/iPS cells PMID: 23717584
CER1 gene variations play a significant role in determining BMD and vertebral or hip fractures, which might be helpful in clinical practice to identify patients with increased fracture risk PMID: 22543871
functional candidate gene for trigonocephaly PMID: 18452192
successful identification of an association with CER1 in humans together with our mouse study suggests that CER1 may play a role in the development of bone or its metabolism PMID: 19113921

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Subcellular Location

Secreted.

Protein Families

DAN family

Database Links

HGNC: 1862

OMIM: 603777

KEGG: hsa:9350

STRING: 9606.ENSP00000370297

UniGene: Hs.248204

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

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Related pathways

Wnt signaling pathway

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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