CHMP7 Antibody

Code CSB-PA005367GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
CHMP7
Alternative Names
CHMP7Charged multivesicular body protein 7 antibody; Chromatin-modifying protein 7 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human CHMP7
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
ESCRT-III-like protein required to recruit the ESCRT-III complex to the nuclear envelope during late anaphase. Together with SPAST, the ESCRT-III complex promotes nuclear envelope sealing and mitotic spindle disassembly during late anaphase. Plays a role in the endosomal sorting pathway.
Gene References into Functions
  1. We conclude that Lem2p/LEM2 is a conserved nuclear site-specific adaptor that recruits Cmp7p/CHMP7 and downstream ESCRT factors to the nuclear envelope. PMID: 28242692
  2. The N terminus of CHMP7 acts as a novel membrane-binding module. This membrane-binding ability allows CHMP7 to bind to the endoplasmic reticulum, an organelle continuous with the nuclear envelope (NE), and it provides a platform to direct NE recruitment of ESCRT-III during mitotic exit. PMID: 27618263
  3. Results suggest that CHMP7, a novel CHMP4-associated ESCRT-III-related protein, functions in the endosomal sorting pathway. PMID: 16856878
Subcellular Location
Cytoplasm. Nucleus envelope.
Protein Families
SNF7 family
Database Links

HGNC: 28439

OMIM: 611130

KEGG: hsa:91782

STRING: 9606.ENSP00000324491

UniGene: Hs.5019

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