CKMT2 Antibody

Code CSB-PA004121
Size US$100
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  • Western Blot analysis of A549 cells using sMtCK Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
CKMT2
Alternative Names
CKMT 2 antibody; Basic-type mitochondrial creatine kinase antibody; CKMT2 antibody; CPK antibody; Creatine kinase mitochondrial 2 antibody; Creatine kinase mitochondrial 2 (sarcomeric) antibody; Creatine kinase S-type antibody; creatine kinase S-type, mitochondrial antibody; Creatine kinase, sarcomeric mitochondrial antibody; KCRS_HUMAN antibody; Mib CK antibody; Mib-CK antibody; mitochondrial antibody; OTTHUMP00000147542 antibody; S-MtCK antibody; Sarcomeric mitochondrial creatine kinase antibody; SMTCK antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from the Internal region of Human sMtCK.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, IF, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:40000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
Gene References into Functions
  1. three C-terminal lysines determine high affinity sMtCK/cardiolipin interaction and its effects on MtCK structure, whereas low level binding and some effect on membrane fluidity depend on other structural components PMID: 15044463
  2. After the training period, intracellular energetic units had a higher control of mitochondrial respiration by creatine linked to a more efficient functional coupling adenine nucleotide translocase-mitochondrial creatine kinase. PMID: 16020522
  3. CK2alpha has a role in progression of acute myeloid leukemia PMID: 17289898
Subcellular Location
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein Families
ATP:guanido phosphotransferase family
Tissue Specificity
Sarcomere-specific. Found only in heart and skeletal muscles.
Database Links

HGNC: 1996

OMIM: 123295

KEGG: hsa:1160

STRING: 9606.ENSP00000254035

UniGene: Hs.80691

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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