CKMT2 Antibody

Code CSB-PA005462ESR2HU
Size US$166
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  • Western blot
    All lanes: CKMT2 antibody at 6μg/ml + Hela whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 48 kDa
    Observed band size: 48 kDa

  • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA005462ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CKMT2 Polyclonal antibody
Uniprot No.
Target Names
CKMT2
Alternative Names
CKMT 2 antibody; Basic-type mitochondrial creatine kinase antibody; CKMT2 antibody; CPK antibody; Creatine kinase mitochondrial 2 antibody; Creatine kinase mitochondrial 2 (sarcomeric) antibody; Creatine kinase S-type antibody; creatine kinase S-type, mitochondrial antibody; Creatine kinase, sarcomeric mitochondrial antibody; KCRS_HUMAN antibody; Mib CK antibody; Mib-CK antibody; mitochondrial antibody; OTTHUMP00000147542 antibody; S-MtCK antibody; Sarcomeric mitochondrial creatine kinase antibody; SMTCK antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Creatine kinase S-type, mitochondrial protein (40-230AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
Gene References into Functions
  1. three C-terminal lysines determine high affinity sMtCK/cardiolipin interaction and its effects on MtCK structure, whereas low level binding and some effect on membrane fluidity depend on other structural components PMID: 15044463
  2. After the training period, intracellular energetic units had a higher control of mitochondrial respiration by creatine linked to a more efficient functional coupling adenine nucleotide translocase-mitochondrial creatine kinase. PMID: 16020522
  3. CK2alpha has a role in progression of acute myeloid leukemia PMID: 17289898
Subcellular Location
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein Families
ATP:guanido phosphotransferase family
Tissue Specificity
Sarcomere-specific. Found only in heart and skeletal muscles.
Database Links

HGNC: 1996

OMIM: 123295

KEGG: hsa:1160

STRING: 9606.ENSP00000254035

UniGene: Hs.80691

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