CST5 Antibody, Biotin conjugated

Code CSB-PA006093LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CST5 Polyclonal antibody
Uniprot No.
Target Names
CST5
Alternative Names
CST 5 antibody; CST5 antibody; Cystatin 5 antibody; Cystatin-5 antibody; Cystatin-D antibody; CystatinD antibody; Cysteine proteinase inhibitor antibody; CYTD_HUMAN antibody; MGC71922 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Cystatin-D protein (21-142AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Cysteine proteinase inhibitor that possibly plays a protective role against proteinases present in the oral cavity. The order of preference for inhibition is cathepsin S > cathepsin H > cathepsin L > cathepsin B.
Gene References into Functions
  1. Results imply CST5 as an important mediator of tumor suppression by p53 in colorectal cancer. PMID: 26158294
  2. These results support an unanticipated role of cystatin D in the cell nucleus, controlling the transcription of specific genes involved in crucial cellular functions, which may mediate its protective action in colon cancer. PMID: 26364852
  3. Compared with its homologues, cystatin D presents an unusual inhibition profile with a preferential inhibition cathepsin S > cathepsin H > cathepsin L and no inhibition of cathepsin B or pig legumain. PMID: 15728581
  4. Cystatin D is a candidate tumor suppressor gene induced by vitamin D in human colon cancer cells. PMID: 19662683
Subcellular Location
Secreted.
Protein Families
Cystatin family
Tissue Specificity
Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in parotid gland but not in seminal vesicle, prostate, epididymis, testis, ovary, placenta, thyroid, gastric corpus, small intestine, liver, or gall b
Database Links

HGNC: 2477

OMIM: 123858

KEGG: hsa:1473

STRING: 9606.ENSP00000307132

UniGene: Hs.121489

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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