CTPS2 Antibody

Code CSB-PA865117EA01HU
Size US$166
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  • Immunoprecipitating CTPS2 in HepG2 whole cell lysate
    Lane 1: Rabbit control IgG instead of CSB-PA865117EA01HU in HepG2 whole cell lysate. For western blotting, a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000)
    Lane 2: CSB-PA865117EA01HU (6µg) + HepG2 whole cell lysate (500µg)
    Lane 3: HepG2 whole cell lysate (20µg)

  • Western Blot
    Positive WB detected in: HepG2 whole cell lysate
    All lanes: CTPS2 antibody at 2.8µg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 66 kDa
    Observed band size: 66 kDa

  • Immunocytochemistry analysis of human gastric cancer using CSB-PA865117EA01HU at dilution of 1:100

  • Immunocytochemistry analysis of human prostate tissue using CSB-PA865117EA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CTPS2 Polyclonal antibody
Uniprot No.
Target Names
CTPS2
Alternative Names
CTP synthase 2 antibody; CTP synthase II antibody; CTP synthetase 2 antibody; CTPS2 antibody; CYTIDINE 5 PRIME TRIPHOSPHATE SYNTHETASE 2 antibody; FLJ43358 antibody; MGC32997 antibody; PYRG2_HUMAN antibody; UTP--ammonia ligase 2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human CTP synthase 2 protein (62-315AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The CTPS2 Antibody (Product code: CSB-PA865117EA01HU) is Non-conjugated. For CTPS2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA865117EB01HU CTPS2 Antibody, HRP conjugated ELISA
FITC CSB-PA865117EC01HU CTPS2 Antibody, FITC conjugated
Biotin CSB-PA865117ED01HU CTPS2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC, IP
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
IP 1:200-1:2000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides.
Gene References into Functions
  1. CTPS2 was identified by genome-wide gene expression analyses as correlated with cellular sensitivity to cisplatin and carboplatin. PMID: 21252287
  2. Low CTPS2 expression may be a rationally-based determinant of 5FU resistance. PMID: 21378502
  3. analysis of the kinetic properties of hCTPS1 and hCTPS2, and determination that Ser(68) is a major site of CTPS2 regulation by phosphorylation PMID: 20739275
Protein Families
CTP synthase family
Database Links

HGNC: 2520

OMIM: 300380

KEGG: hsa:56474

STRING: 9606.ENSP00000352222

UniGene: Hs.227049

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