CWC27 Antibody

Code CSB-PA020896GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
CWC27
Alternative Names
Antigen NY CO10 antibody; Antigen NY-CO-10 antibody; CWC27 antibody; CWC27 spliceosome associated protein homolog (S. cerevisiae) antibody; CWC27 spliceosome associated protein homolog S cerevisiae antibody; CWC27_HUMAN antibody; NY CO 10 antibody; NY-CO-10 antibody; peptidyl prolyl cis trans isomerase CWC27 homolog antibody; Peptidyl prolyl cis trans isomerase SDCCAG10 antibody; Peptidyl-prolyl cis-trans isomerase CWC27 homolog antibody; PPIase CWC27 antibody; PPIase SDCCAG10 antibody; SDCCAG10 antibody; Serologically defined colon cancer antigen 10 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human SDCCAG10
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
As part of the spliceosome, plays a role in pre-mRNA splicing. Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity.
Gene References into Functions
  1. CWC27 overexpression is associated with Bladder Cancer. PMID: 27206850
  2. By whole-exome sequencing, recessive protein-truncating mutations in CWC27 were found in seven unrelated families that show a range of clinical phenotypes, including retinal degeneration, brachydactyly, craniofacial abnormalities, short stature, and neurologic defects. PMID: 28285769
  3. The crystal structure of a relatively protease-resistant N-terminal fragment of human Cwc27 containing the cyclophilin-type peptidyl-prolyl cis-trans isomerase domain was determined at 2.0 A resolution. PMID: 25478830
Involvement in disease
Retinitis pigmentosa with or without skeletal anomalies (RPSKA)
Subcellular Location
Nucleus.
Protein Families
Cyclophilin-type PPIase family
Database Links

HGNC: 10664

OMIM: 250410

KEGG: hsa:10283

STRING: 9606.ENSP00000370460

UniGene: Hs.371372

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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