CWC27 Antibody

Datasheet

Code	CSB-PA972891
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA972891(CWC27 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200) Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Human liver cancer tissue, Human normal colon tissue, human placenta tissue, Primary antibody: CSB-PA972891(CWC27 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q6UX04

Target Names

CWC27

Alternative Names

Antigen NY CO10 antibody; Antigen NY-CO-10 antibody; CWC27 antibody; CWC27 spliceosome associated protein homolog (S. cerevisiae) antibody; CWC27 spliceosome associated protein homolog S cerevisiae antibody; CWC27_HUMAN antibody; NY CO 10 antibody; NY-CO-10 antibody; peptidyl prolyl cis trans isomerase CWC27 homolog antibody; Peptidyl prolyl cis trans isomerase SDCCAG10 antibody; Peptidyl-prolyl cis-trans isomerase CWC27 homolog antibody; PPIase CWC27 antibody; PPIase SDCCAG10 antibody; SDCCAG10 antibody; Serologically defined colon cancer antigen 10 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide of Human CWC27

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,WB,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:1000-1:2000
WB	1:200-1:1000
IHC	1:25-1:100

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

As part of the spliceosome, plays a role in pre-mRNA splicing. Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity.

Gene References into Functions

CWC27 overexpression is associated with Bladder Cancer. PMID: 27206850
By whole-exome sequencing, recessive protein-truncating mutations in CWC27 were found in seven unrelated families that show a range of clinical phenotypes, including retinal degeneration, brachydactyly, craniofacial abnormalities, short stature, and neurologic defects. PMID: 28285769
The crystal structure of a relatively protease-resistant N-terminal fragment of human Cwc27 containing the cyclophilin-type peptidyl-prolyl cis-trans isomerase domain was determined at 2.0 A resolution. PMID: 25478830

Involvement in disease

Retinitis pigmentosa with or without skeletal anomalies (RPSKA)

Subcellular Location

Nucleus.

Protein Families

Cyclophilin-type PPIase family

Database Links

HGNC: 10664

OMIM: 250410

KEGG: hsa:10283

STRING: 9606.ENSP00000370460

UniGene: Hs.371372

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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