CYP7A1 Antibody, Biotin conjugated

Datasheet
Code CSB-PA006460LD01HU
Size US$299
Uniprot No. P22680
Protocols ELISA Protocol
Immunogen Recombinant Human Cholesterol 7-alpha-monooxygenase protein (303-423AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis.
Form Liquid
Conjugate Biotin
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Cholesterol 7-alpha-monooxygenase (EC 1.14.14.23) (CYPVII) (Cholesterol 7-alpha-hydroxylase) (Cytochrome P450 7A1), CYP7A1, CYP7
Immunogen Species Homo sapiens (Human)
Research Area Cardiovascular
Target Names CYP7A1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis.
Subcellular Location Endoplasmic reticulum membrane, Peripheral membrane protein, Microsome membrane, Peripheral membrane protein
Protein Families Cytochrome P450 family
Tissue Specificity Detected in liver.
Database Links

HGNC: 2651

OMIM: 118455

KEGG: hsa:1581

STRING: 9606.ENSP00000301645

UniGene: Hs.1644

Pathway PPAR signaling pathway
Cholesterol metabolism

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