Cd82 Antibody, FITC conjugated

Code CSB-PA004961LC01MO
Size US$299
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Product Details

Full Product Name Rabbit anti-Mus musculus (Mouse) Cd82 Polyclonal antibody
Uniprot No. P40237
Target Names Cd82
Alternative Names Cd82 antibody; Kai1CD82 antigen antibody; C33 antigen antibody; IA4 antibody; Inducible membrane protein R2 antibody; Metastasis suppressor Kangai-1 homolog antibody; CD antigen CD82 antibody
Raised in Rabbit
Species Reactivity Mouse
Immunogen Recombinant Mouse CD82 antigen protein (111-227AA)
Immunogen Species Mus musculus (Mouse)
Conjugate FITC
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form Liquid
Tested Applications ELISA
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Data

Function Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway.
Gene References into Functions
  1. The CD82 is a functional surface marker of long-term repopulating hematopoietic stem cells (LT-HSCs) that maintains quiescence through interaction with DARC-expressing macrophages in the bone marrow stem cell niche. PMID: 26996598
  2. Loss of Kai1 expression is associated with neoplasm metastasis. PMID: 23401136
  3. The synergistic effects of CD82 and GM3 or GM2/GM3 ganglioside on EGFR expression and phosphorylation and cMet activation are responsible for CD82 inhibition of EGF- and HGF-dependent cell motility and migration of Hepa1-6 cells. PMID: 23968914
  4. the CD82 tetraspanin is specifically recruited to pathogen-containing phagosomes prior to fusion with lysosomes. PMID: 21149584
  5. KAI1 has a role in promotion of cell proliferation and mammary gland hyperplasia by the gp78 ubiquitin ligase PMID: 20089858
  6. Hypoxia-dependent induction of KAI1 was directly mediated by hypoxia-inducible factor-1alpha binding on the promoter, which subsequently caused increased recruitment of RNA polymerase II for transcriptional activation. PMID: 20123085
  7. An antibody to this protein that can specifically detect murine Kai1/CD82, should be useful in addressing the mechanism of action of Kai1 in metastatic suppression. PMID: 16372335
  8. gp78 promotes sarcoma metastasis by targeting KAI1 for degradation PMID: 18037895
  9. The transgenic adenocarcinoma of mouse prostate model encompasses androgen depletion independent sublines with increased tumorigenicity and invasiveness. All showed downregulation in tumor suppressor, E-cadherin, and metastatis suppressor, KAI-1. PMID: 18247402

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Subcellular Location Membrane, Multi-pass membrane protein
Protein Families Tetraspanin (TM4SF) family
Tissue Specificity Highest expression in the spleen and the kidney. Low expression in skeletal muscle and in the heart.
Database Links

KEGG: mmu:12521

STRING: 10090.ENSMUSP00000028644

UniGene: Mm.4261

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