Cleaved-F7 (R212) Antibody

Datasheet
Code CSB-PA000066
Size US$167
Uniprot No. P08709
Image
  • Western Blot analysis of Jurkat cells using Cleaved-Factor VII LC (R212) Polyclonal Antibody
Protocols Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
ELISA Protocol
Immunogen Synthesized peptide derived from the Internal region of Human Factor VII LC.
Raised in Rabbit
Species Reactivity Human
Tested Applications WB,IHC,ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/20000
Form Liquid
Conjugate Non-conjugated
Storage Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Alias F7; Coagulation factor VII; Proconvertin; Serum prothrombin conversion accelerator; SPCA; Eptacog alfa
Immunogen Species Homo sapiens (Human)
Target Names F7
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.
Involvement in disease Factor VII deficiency (FA7D)
Subcellular Location Secreted
Protein Families Peptidase S1 family
Tissue Specificity Plasma.
Database Links

HGNC: 3544

OMIM: 227500

KEGG: hsa:2155

STRING: 9606.ENSP00000364731

UniGene: Hs.36989

Pathway Complement and coagulation cascades

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