Cleaved-ITIH2 (D702) Antibody

Code CSB-PA000075
Size US$100
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  • Western Blot analysis of 293 cells using Cleaved-ITI-H2 (D702) Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
ITIH2
Alternative Names
AI747202 antibody; H2P antibody; IGHEP2 antibody; Inter alpha (globulin) inhibitor H2 antibody; Inter alpha globulin inhibitor H2 polypeptide antibody; Inter alpha trypsin inhibitor complex component II antibody; Inter alpha trypsin inhibitor heavy chain H2 antibody; Inter-alpha-inhibitor heavy chain 2 antibody; Inter-alpha-trypsin inhibitor complex component II antibody; Inter-alpha-trypsin inhibitor heavy chain H2 antibody; Intin2 antibody; ITI HC2 antibody; ITI heavy chain H2 antibody; ITI-HC2 antibody; Itih 2 antibody; Itih2 antibody; ITIH2_HUMAN antibody; OTTHUMP00000019058 antibody; OTTHUMP00000019059 antibody; OTTMUSP00000012019 antibody; RP23 119N4.3 antibody; Serum derived hyaluronan associated protein antibody; Serum-derived hyaluronan-associated protein antibody; SHAP antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of Human ITI-H2.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:10000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
Gene References into Functions
  1. It forms complex with hyaluronan and the comlex is a functional molecule involved in inflammation. PMID: 20297716
  2. TSG-6 acts as cofactor and catalyst in the production of IalphaI heavy chain x hyaluronan complexes PMID: 15840581
  3. Leukocytes infiltrated to the synovium were strongly positive for hyaluronic acid, SHAP, and CD44 on their surfaces, suggesting a role for the adhesion-enhancing effect of SHAP in inflammation. PMID: 16702221
  4. Increased levels of SHAP-HA complex in sera are possible predictive markers for cervical ripening in premature labor. PMID: 18382897
  5. serum-derived hyaluronan-associated protein-hyaluronan complex has a role in progression of ovarian cancer PMID: 18425383

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Subcellular Location
Secreted.
Protein Families
ITIH family
Tissue Specificity
Plasma.
Database Links

HGNC: 6167

OMIM: 146640

KEGG: hsa:3698

STRING: 9606.ENSP00000351190

UniGene: Hs.75285

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