DCTN4 Antibody

Datasheet

Code	CSB-PA892445LA01HU
Size	US$166
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Image	Western Blot Positive WB detected in: HepG2 whole cell lysate, Jurkat whole cell lysate, HEK293 whole cell lysate, SH-SY5Y whole cell lysate All lanes: DCTN4 antibody at 3.4μg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 53, 46, 54 kDa Observed band size: 53 kDa
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) DCTN4 Polyclonal antibody

Uniprot No.

Q9UJW0

Target Names

DCTN4

Alternative Names

DCTN 4 antibody; Dctn4 antibody; DCTN4_HUMAN antibody; Dynactin 4 (p62) antibody; Dynactin 4 antibody; Dynactin p62 subunit antibody; Dynactin subunit 4 antibody; Dynactin subunit p62 antibody; Dynactin4 antibody; p62 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Dynactin subunit 4 protein (2-460AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The DCTN4 Antibody (Product code: CSB-PA892445LA01HU) is Non-conjugated. For DCTN4 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA892445LB01HU	DCTN4 Antibody, HRP conjugated	ELISA
FITC	CSB-PA892445LC01HU	DCTN4 Antibody, FITC conjugated
Biotin	CSB-PA892445LD01HU	DCTN4 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.

Gene References into Functions

Findings provide evidence that DCTN4 missense variants, especially p.Tyr263Cys, may be involved in the pathogenesis of chronic Pseudomonas aeruginosa infection in male with cystic fi brosis. PMID: 25763772
used an extreme phenotype study to discover that variants in DCTN4, encoding a dynactin protein, are associated with time to first P. aeruginosa airway infection, chronic P. aeruginosa infection and mucoid P. aeruginosa in individuals with cystic fibrosis PMID: 22772370
ATP7B interaction with p62 is a key component of the copper-induced trafficking pathway that delivers ATP7B to subapical vesicles of hepatocytes for the removal of excess copper into bile PMID: 16554302

Subcellular Location

Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, stress fiber. Cytoplasm, cell cortex. Cytoplasm, myofibril, sarcomere.

Protein Families

Dynactin subunit 4 family

Database Links

HGNC: 15518

OMIM: 614758

KEGG: hsa:51164

STRING: 9606.ENSP00000414906

UniGene: Hs.675564

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Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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