DECR1 Antibody

Datasheet

Code	CSB-PA087606
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA087606(DECR1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA087606(DECR1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200) Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-4: Human endometrial carcinoma tissue, Human colon cancer tissue, human fetal liver tissue, PC3 cells, Primary antibody: CSB-PA087606(DECR1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
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Product Details
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Target Background

Product Details

Uniprot No.

Q16698

Target Names

DECR1

Alternative Names

1200012F07Rik antibody; 2 antibody; 2,4 dienoyl CoA reductase [NADPH] antibody; 2,4 dienoyl CoA reductase 1 antibody; 2,4 dienoyl CoA reductase mitochondrial antibody; 2,4-dienoyl-CoA reductase; mitochondrial antibody; 4 enoyl CoA reductase antibody; 4-dienoyl-CoA reductase [NADPH] antibody; 4-enoyl-CoA reductase [NADPH] antibody; DECR 1 antibody; DECR antibody; DECR_HUMAN antibody; DECR1 antibody; Nadph antibody; OTTMUSP00000004962 antibody; RP23-338J24.3 antibody; SDR18C1 antibody; Short chain dehydrogenase/reductase family 18C member 1 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide of Human DECR1

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,WB,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:2000-1:5000
WB	1:500-1:2000
IHC	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in mitochondria. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA.

Gene References into Functions

Our study is the first to demonstrate the novel function of UA in NET formation and may provide insight into the management of patients with hyperuricemia. PMID: 24326071
Structure and reactivity of human mitochondrial 2,4-dienoyl-CoA reductase PMID: 15531764
Sequence alignment indicates that there are five highly conserved acidic residues, one of which (E276) might act as a proton donor. PMID: 15629123
mutational defects cause chronic granulomatous disease in humans PMID: 18193341
The luminal NADPH pool is an important antiapoptotic factor in neutrophil granulocytes. PMID: 18472006
The TT genotype of C677T polymorphism in the MTHFR gene contributes to genetic susceptibility of acute ischemic stroke in a Singapore population. PMID: 19049547

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Involvement in disease

2,4-dienoyl-CoA reductase deficiency (DECRD)

Subcellular Location

Mitochondrion.

Protein Families

Short-chain dehydrogenases/reductases (SDR) family, 2,4-dienoyl-CoA reductase subfamily

Tissue Specificity

Heart = liver = pancreas > kidney >> skeletal muscle = lung.

Database Links

HGNC: 2753

OMIM: 222745

KEGG: hsa:1666

STRING: 9606.ENSP00000220764

UniGene: Hs.492212

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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