DNAL4 Antibody

Code CSB-PA007046LA01HU
Size US$166
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  • Western blot
    All lanes: DNAL4 antibody at 1.5µg/ml
    Lane 1: Mouse gonadal tissue
    Lane 2: HL60 whole cell lysate
    Lane 3: NIH/3T3 whole cell lysate
    Lane 4: Mouse brain tissue
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 13 kDa
    Observed band size: 13 kDa

  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA007046LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA007046LA01HU at dilution of 1:100

  • Immunofluorescent analysis of MCF-7 cells using CSB-PA007046LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) DNAL4 Polyclonal antibody
Uniprot No.
Target Names
DNAL4
Alternative Names
D15Ertd424e antibody; Dnal4 antibody; DNAL4_HUMAN antibody; Dnalc4 antibody; Dynein axonemal light chain 4 antibody; Dynein light chain 4; axonemal antibody; Dynein light chain; outer arm 4 antibody; Dynein; axonemal; light 4 antibody; Dynein; axonemal; light polypeptide 4 antibody; MGC105573 antibody; PIG27 antibody; Proliferation inducing gene 27 antibody; Proliferation inducing protein 27 antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Dynein light chain 4, axonemal protein (1-105AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The DNAL4 Antibody (Product code: CSB-PA007046LA01HU) is Non-conjugated. For DNAL4 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA007046LB01HU DNAL4 Antibody, HRP conjugated ELISA
FITC CSB-PA007046LC01HU DNAL4 Antibody, FITC conjugated
Biotin CSB-PA007046LD01HU DNAL4 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Description

CUSABIO uses the recombinant human DNAL4 protein (1-105AA) to immunize rabbits and then purify the rabbit antiserum through antigen affinity purification to obtain the anti-DNAL4 antibody. This DNAL4 antibody is a polyclonal antibody and occurs as an unconjugated IgG. It shows reactivity with human and mouse DNAL4 protein, a component of the outer dynein arms complex which acts as the molecular motor to provide the force to move cilia in an ATP-dependent manner. And this anti-DNAL4 antibody can be used in ELISA, WB, IHC, and IF for the detection of the DNAL4 protein.

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Target Background

Function
Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity.
Gene References into Functions
  1. No mutation in DNAL4 in Congenital mirror movements. PMID: 25236653
  2. DNAL4 may play a role in the cytoplasmic dynein complex for netrin-1-directed retrograde transport, and in commissural neurons of the corpus callosum in particular. This could lead to faulty cross-brain wiring, resulting in Mirror movements (MRMV). PMID: 25098561
Involvement in disease
Mirror movements 3 (MRMV3)
Subcellular Location
Cytoplasm, cytoskeleton, cilium axoneme.
Protein Families
Dynein light chain family
Database Links

HGNC: 2955

OMIM: 610565

KEGG: hsa:10126

STRING: 9606.ENSP00000216068

UniGene: Hs.632766

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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