DOK6 Antibody

Datasheet

Code	CSB-PA007112LA01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) DOK6 Polyclonal antibody

Uniprot No.

Q6PKX4

Target Names

DOK6

Alternative Names

DOK6 antibody; DOK5LDocking protein 6 antibody; Downstream of tyrosine kinase 6 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Docking protein 6 protein (109-331AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The DOK6 Antibody (Product code: CSB-PA007112LA01HU) is Non-conjugated. For DOK6 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA007112LB01HU	DOK6 Antibody, HRP conjugated	ELISA
FITC	CSB-PA007112LC01HU	DOK6 Antibody, FITC conjugated
Biotin	CSB-PA007112LD01HU	DOK6 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK6 promotes Ret-mediated neurite growth. May have a role in brain development and/or maintenance.

Gene References into Functions

DOK-6 is involved in RET signaling with less influence when compared with DOK-1, DOK-4, and SHC. PMID: 20210798
Dok-6 binds to the phosphorylated Ret Tyr(1062) residue resulting in phosphorylation of tyrosine residue(s) located within the unique C terminus of Dok-6 predominantly through a Src-dependent mechanism PMID: 15286081

Protein Families

DOK family, Type B subfamily

Tissue Specificity

Highly expressed in fetal and adult brain. Highly expressed in the cerebellum. Weak expression in kidney, spinal cord and testis.

Database Links

HGNC: 28301

OMIM: 611402

KEGG: hsa:220164

STRING: 9606.ENSP00000372160

UniGene: Hs.278285

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Phage Display Service

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Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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