DPPA2 Antibody

Code CSB-PA007144GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
DPPA2
Alternative Names
DPPA2 antibody; PESCRG1Developmental pluripotency-associated protein 2 antibody; Pluripotent embryonic stem cell-related gene 1 protein antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Human ECSA
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Binds to target gene promoters, including NKX2-5 and SYCE1, but not GATA4, and may be involved in the maintenance of the active epigenetic status of these genes.
Gene References into Functions
  1. High DPPA2 Protein Expression is Associated with Gastric Cancer Metastasis PMID: 26745102
  2. results showed that DPPA2 expression was significantly correlated to the depth of tumor invasion and progression of tumor cells through advanced stages in colorectal cancer. PMID: 25497006
  3. A important role of HIWI and DPPA2 in tumorigenesis and also in lymph node metastasis of tumor cells. PMID: 24532429
  4. Differential expression of the embryo/cancer gene ECSA(DPPA2) in human preimplantation development. PMID: 18467432
  5. ECSA/DPPA2 is a promising target for antigen-specific immunotherapy in non-small cell lung cancers PMID: 18519755
  6. In normal tissues, PLAC1 expression was restricted to the placenta while DPPA2 expression was restricted to the placenta and testis. PMID: 19705800

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Subcellular Location
Nucleus.
Tissue Specificity
Expressed in embryonic stem cells. No expression is seen in 5 months embryo, mesenchymal stem cells, embryonic fibrocytes and adult tissues.
Database Links

HGNC: 19197

OMIM: 614445

KEGG: hsa:151871

STRING: 9606.ENSP00000417710

UniGene: Hs.351113

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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