DPPA3 Antibody, Biotin conjugated

1. Super-enhancers at the Nanog locus differentially regulate neighboring pluripotency-associated genes, in particular, DPPA3. PMID: 27681417
2. We conclude that heterogeneous population of the HEK293T cells might be easily shifted towards expression of the pluripotency markers by ectopic expression of the SON factors or by growth in serum depleted media. PMID: 27794480
3. Data suggest enforced expression of Stella into normal cells induces not only global DNA demethylation but also neoplastic transformation and increases metastatic ability; these changes involve altered regulation of neoplastic gene expression. PMID: 26608031
4. Considering that impaired DNA methylation profiles are associated with various developmental or disease phenomena, Stella may be a powerful tool with which to study the biological effects of global DNA hypomethylation PMID: 25280994
5. a role for STELLA in facilitating germline and endodermal differentiation of human ES cells PMID: 23457636
6. human adult tissue-specific transcripts originate via retrotransposition of the pluripotent cell-specific gene, Dppa3 PMID: 16291741
7. These results demonstrate that PGC7/Stella is indispensable for the maintenance of methylation involved in epigenetic reprogramming after fertilization. PMID: 17143267
8. In mice, this gene may play a role in oogenesis and primordial germ cell development. PMID: 11900980
9. In mice, a targeted mutation results in reduced female fertility and may function as a mammalian maternal effect gene. PMID: 14654002
10. In mice, knockout experiments show this gene may be a maternal factor in cleavage stage embryogenesis. PMID: 15018652

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HGNC: 19199

OMIM: 608408

KEGG: hsa:359787

STRING: 9606.ENSP00000339250

UniGene: Hs.131358