DSTYK Antibody

Datasheet

Code	CSB-PA007213GA01HU
Size	$600
	Order now
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q6XUX3

Target Names

DSTYK

Alternative Names

DSTYK antibody; Dual serine/threonine and tyrosine protein kinase antibody; Dusty PK antibody; Dusty protein kinase antibody; DUSTY_HUMAN antibody; HDCMD38P antibody; KIAA0472 antibody; Receptor interacting protein 5 antibody; Receptor interacting protein kinase 5 antibody; Receptor interacting serine/threonine protein kinase 5 antibody; Receptor-interacting serine/threonine-protein kinase 5 antibody; RIP homologous kinase antibody; RIP-homologous kinase antibody; RIP5 antibody; RIPK5 antibody; SgK496 antibody; Sugen kinase 496 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human DSTYK

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB,IF

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

■ Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function

Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. Involved in the regulation of both caspase-dependent apoptosis and caspase-independent cell death. In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types.

Gene References into Functions

RIPK3 promotes adenovirus type 5 oncolytic activity. PMID: 29238045
we identified a complex homozygous 4-kb deletion/20-bp insertion in DSTYK in all four affected family members with Autosomal-Recessive Complicated Spastic Paraparesis, SPG23 PMID: 28157540
We detected independent DSTYK mutations in 2.3% of patients with congenital abnormalities of the kidney or urinary tract, a finding that suggests that DSTYK is a major determinant of human urinary tract development, downstream of FGF signaling. PMID: 23862974
Confocal imaging of transiently expressed human Dusty-GFP fusion proteins showed a cytoplasmic distribution. PMID: 17123648

Involvement in disease

Congenital anomalies of the kidney and urinary tract 1 (CAKUT1); Spastic paraplegia 23 (SPG23)

Subcellular Location

Cytoplasm. Cell membrane. Apical cell membrane. Basolateral cell membrane. Cell junction.

Protein Families

Protein kinase superfamily, Ser/Thr protein kinase family

Tissue Specificity

Predominantly expressed in skeletal muscle and testis. Expressed in basolateral and apical membranes of all tubular epithelia. Expressed in thin ascending limb of the loop of Henle and the distal convoluted tubule. Expressed in all layers of transitional

Database Links

HGNC: 29043

OMIM: 270750

KEGG: hsa:25778

STRING: 9606.ENSP00000356130

UniGene: Hs.6874

Promotions

Transmembrane Protein Questionnaire with Gifts

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

Join us with

Subscribe newsletter

Leave a message

Message

Product >> Product Name：
Product >> Code：
Name： *
Email： *
Company/Organization：
Phone：
Since emails may get flagged by spam filters occasionally, we recommend leaving your phone number as a precaution. Your information is safe with us.
Question/Comment： *
Your Region： *
I'd like to receive email newsletters from Cusabio

Yes

No
How do you know CUSABIO?

Email

Distributor

Search engine

Advertisement

Others
CAPTCHA verification：

Place an order now

I. Product details

Product name *

Code *

Size *

Quantity *

Message

II. Contact details

Name *

Email address *

Company/Organization

Phone

III. Ship To

Address *

City *

State/Province *

Zip/Post code *

Country *

Attn Name *

Phone# *

IV. Bill To Same as Shipping Address