DTX2 Antibody

Datasheet

Code	CSB-PA803123ESR2HU
Size	US$166
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Image	Western blot All lanes: DTX2 antibody at 1μg/ml + HepG2 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 68, 63 kDa Observed band size: 68, 92 kDa Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA803123ESR2HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) DTX2 Polyclonal antibody

Uniprot No.

Q86UW9

Target Names

DTX2

Alternative Names

Deltex 2 antibody; deltex homolog 2 (Drosophila) antibody; deltex; Drosophila; homolog of; 2 antibody; Deltex2 antibody; DTX2 antibody; DTX2_HUMAN antibody; hDTX2 antibody; Highly similar to hPMSR6 [H.sapiens] antibody; KIAA1528 antibody; Probable E3 ubiquitin-protein ligase DTX2 antibody; Protein deltex 2 antibody; Protein deltex-2 antibody; RING finger protein 58 antibody; RNF58 antibody; Zinc ion binding protein antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Probable E3 ubiquitin-protein ligase DTX2 protein (1-280AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

Gene References into Functions

DTX2 is a gene encoding a WWE-RING-finger protein and involved in regulating heart development and heart functions. PMID: 17286044
It is reported that BBAP and the human family of DTX proteins (DTX1, DTX2, and DTX3) function as E3 ligases based on their capacity for self-ubiquitination. PMID: 12670957

Subcellular Location

Cytoplasm. Nucleus.

Protein Families

Deltex family

Database Links

HGNC: 15973

OMIM: 613141

KEGG: hsa:113878

STRING: 9606.ENSP00000322885

UniGene: Hs.187058

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Service

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Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Notch signaling pathway

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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