ECI2 Antibody

Datasheet

Code	CSB-PA527983LA01HU
Size	US$166
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Image	Western Blot Positive WB detected in: Rat heart tissue, Mouse heart tissue, Mouse liver tissue All lanes: ECI2 antibody at 2.7μg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 44, 40 kDa Observed band size: 44 kDa Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA527983LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ECI2 Polyclonal antibody

Uniprot No.

O75521

Target Names

ECI2

Alternative Names

2-trans-enoyl-CoA isomerase antibody; ACBD2 antibody; acyl Coenzyme A binding domain containing 2 antibody; D2-enoyl-CoA isomerase antibody; D3 antibody; D3 D2 enoyl CoA isomerase antibody; DBI related protein 1 antibody; DBI-related protein 1 antibody; delta(2)-enoyl-CoA isomerase antibody; Delta(3) antibody; Delta(3) delta(2) enoyl CoA isomerase antibody; Diazepam-binding inhibitor-related protein 1 antibody; Dodecenoyl CoA isomerase antibody; Dodecenoyl-CoA isomerase antibody; DRS 1 antibody; DRS-1 antibody; DRS1 antibody; Eci2 antibody; ECI2_HUMAN antibody; Enoyl-CoA delta isomerase 2 antibody; HCA88 antibody; Hepatocellular carcinoma associated antigen 88 antibody; Hepatocellular carcinoma-associated antigen 88 antibody; mitochondrial antibody; pECI antibody; Peroxisomal 3 antibody; Peroxisomal 3,2-trans-enoyl-CoA isomerase antibody; Peroxisomal D3 D2 enoyl CoA isomerase antibody; Renal carcinoma antigen NY REN 1 antibody; Renal carcinoma antigen NY-REN-1 antibody

Raised in

Rabbit

Species Reactivity

Human, Rat, Mouse

Immunogen

Recombinant Human Enoyl-CoA delta isomerase 2, mitochondrial protein (119-219AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The ECI2 Antibody (Product code: CSB-PA527983LA01HU) is Non-conjugated. For ECI2 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA527983LB01HU	ECI2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA527983LC01HU	ECI2 Antibody, FITC conjugated
Biotin	CSB-PA527983LD01HU	ECI2 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates.

Gene References into Functions

Enoyl-CoA delta isomerase 2 (ECI2) is a novel AR-target that promotes prostate cancer cell survival PMID: 28415728
Ectopic expression of the ACBD2/ECI2 isoform A in MA-10 cells led to increased basal and hormone-stimulated steroid formation, indicating that ACBD2/ECI2-mediated peroxisomes-mitochondria interactions favor in the exchange of metabolites and/or macromolecules between these 2 organelles in support of steroid biosynthesis. Considering the widespread occurrence of the ACBD2/ECI2 protein, we propose that this protein might se PMID: 27167610
Disruption of mitochondrial beta -oxidation of unsaturated fatty acids in the 3,2-trans-enoyl-CoA isomerase-deficient mouse PMID: 11916962
DRS-1 may serve as an autoantigen eliciting immune attack against hematopoietic stem cells in a subset of acquired aplastic anemia patients characterized by increased paroxysmal nocturnal hemoglobinuria-type cells PMID: 15217832

Subcellular Location

[Isoform 1]: Mitochondrion.; [Isoform 2]: Peroxisome matrix.

Protein Families

Enoyl-CoA hydratase/isomerase family

Tissue Specificity

Abundant in heart, skeletal muscle and liver. Expressed in CD34(+) T-cells and CD34(+) bone marrow cells.

Database Links

HGNC: 14601

OMIM: 608024

KEGG: hsa:10455

STRING: 9606.ENSP00000369461

UniGene: Hs.15250

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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