EEF1A1 Antibody, HRP conjugated

Datasheet
Code CSB-PA007409LB01HU
Size US$299
Uniprot No. P68104
Protocols ELISA Protocol
Immunogen Recombinant Human Elongation factor 1-alpha 1 protein (1-462AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production.
Form Liquid
Conjugate HRP
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Elongation factor 1-alpha 1 (EF-1-alpha-1) (Elongation factor Tu) (EF-Tu) (Eukaryotic elongation factor 1 A-1) (eEF1A-1) (Leukocyte receptor cluster member 7), EEF1A1, EEF1A EF1A LENG7
Immunogen Species Human
Research Area Epigenetics and Nuclear Signaling
Target Names EEF1A1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production.
Subcellular Location Cytoplasm, Nucleus, Nucleus, nucleolus, Cell membrane
Protein Families TRAFAC class translation factor GTPase superfamily, Classic translation factor GTPase family, EF-Tu/EF-1A subfamily
Tissue Specificity Brain, placenta, lung, liver, kidney, pancreas but barely detectable in heart and skeletal muscle.
Database Links

HGNC: 3189

OMIM: 130590

KEGG: hsa:1915

STRING: 9606.ENSP00000330054

UniGene: Hs.535192

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