EIF4A2 Antibody

1. eIF4A2 is recruited to stress granules, suggesting sumoylation of eIF4A2 correlates with its recruitment to stress granules. PMID: 27160682
2. expression is an independent prognostic factor for patients with non-small-cell lung cancer for both overall survival and disease-free survival PMID: 23867391
3. These data support a linear model for miRNA-mediated gene regulation in which translational repression via eIF4A2 is required first, followed by mRNA destabilization. PMID: 23559250
4. interacted with NS5B protein, and the two proteins were shown to be partially colocalized in the perinuclear region PMID: 11922617
5. Single nucleotide polymorphisms in two relevant candidate genes for glucose homeostasis, kininogen (KNG1), and eukaryotic translation initiation factor 4alpha2 (EIF4A2) linked to type 2 diabetes. PMID: 16567544
6. subcellular distribution of eIF4F components may potentiate the complex assembly PMID: 18250159
7. A feedforward loop involving c-Myc and eIF4F that serves to link transcription and translation and that could contribute to the effects of c-Myc on cell proliferation and neoplastic growth. PMID: 18593934
8. This protein has been found differentially expressed in the temporal lobe from patients with schizophrenia. PMID: 19034380

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HGNC: 3284

OMIM: 601102

KEGG: hsa:1974

STRING: 9606.ENSP00000326381

UniGene: Hs.518475