ELP4 Antibody, Biotin conjugated

Code CSB-PA853408LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ELP4 Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
C11orf19 antibody; dJ68P15A.1 antibody; elongation protein 4 homolog (S. cerevisiae) antibody; Elongation protein 4 homolog antibody; Elongator complex protein 4 antibody; ELP4 antibody; ELP4_HUMAN antibody; FLJ20498 antibody; hELP4 antibody; PAX6 neighbor gene protein antibody; PAX6NEB antibody; PAXNEB antibody
Raised in
Species Reactivity
Recombinant Human Elongator complex protein 4 protein (117-223AA)
Immunogen Species
Homo sapiens (Human)
Purification Method
>95%, Protein G purified
It differs from different batches. Please contact us to confirm it.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Tested Applications
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
Gene References into Functions
  1. Our results suggest that ELP4 deletions are highly likely to be pathogenic, predisposing to a range of neurodevelopmental phenotypes from ASD to language impairment and epilepsy. PMID: 26010655
  2. Results show no difference in BDNF and ELP4 genotype frequencies between benign epilepsy with centrotemporal spikes patients and controls; haplotype analysis also revealed no statistical difference PMID: 25301525
  3. No association of SNPs in the ELP4 gene was detected in rolandic epilepsy patients. PMID: 24995671
  4. Data suggest that a non-coding mutation in ELP4 impairs brain-specific Elongator-mediated interaction of genes implicated in brain development, resulting in susceptibility to seizures and neurodevelopmental disorders. PMID: 19172991
Involvement in disease
Aniridia 2 (AN2)
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
ELP4 family
Tissue Specificity
Widely expressed.
Database Links

HGNC: 1171

OMIM: 606985

KEGG: hsa:26610

STRING: 9606.ENSP00000298937

UniGene: Hs.175534

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