EPS8L2 Antibody

Datasheet

Code	CSB-PA204841
Size	US$297
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Image	Western blot analysis of extracts from HeLa cells, Jurkat cells and HUVEC cells, using ES8L2 antibody.
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) EPS8L2 Polyclonal antibody

Uniprot No.

Q9H6S3

Target Names

EPS8L2

Alternative Names

Epidermal growth factor receptor kinase substrate 8 like protein 2 antibody; Epidermal growth factor receptor kinase substrate 8-like protein 2 antibody; Epidermal growth factor receptor pathway substrate 8 like protein 2 antibody; Epidermal growth factor receptor pathway substrate 8 related protein 2 antibody; Epidermal growth factor receptor pathway substrate 8-related protein 2 antibody; EPS8 like 2 antibody; EPS8 like protein 2 antibody; EPS8 related protein 2 antibody; EPS8-like protein 2 antibody; EPS8-related protein 2 antibody; EPS8L 2 antibody; EPS8L2 antibody; EPS8R 2 antibody; EPS8R2 antibody; ES8L2_HUMAN antibody; FLJ16738 antibody; FLJ21935 antibody; FLJ22171 antibody; MGC126530 antibody; MGC3088 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Synthesized peptide derived from internal of Human ES8L2.

Immunogen Species

Homo sapiens (Human)

Clonality

Polyclonal

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Tested Applications

ELISA,WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:3000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. In the cochlea, is required for stereocilia maintenance in adult hair cells.

Gene References into Functions

frame-shift variant (c.1014delC; p.Ser339Alafs*15) was identified in EPS8L2, encoding Epidermal growth factor receptor Pathway Substrate 8 L2, a protein of hair cells' stereocilia previously implicated in progressive deafness in the mouse PMID: 26282398

Involvement in disease

Deafness, autosomal recessive, 106 (DFNB106)

Subcellular Location

Cytoplasm. Cell projection, stereocilium.

Protein Families

EPS8 family

Tissue Specificity

Detected in fibroblasts and placenta.

Database Links

HGNC: 21296

OMIM: 614988

KEGG: hsa:64787

STRING: 9606.ENSP00000320828

UniGene: Hs.55016

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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