EPS8L2 Antibody

Code CSB-PA002383
Size US$167
Image
  • Western Blot analysis of Hela cells using Eps8L2 Polyclonal Antibody

  • Western Blot analysis of A549 K562 cells using Eps8L2 Polyclonal Antibody

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Product Details

Uniprot No. Q9H6S3
Target Names EPS8L2
Alternative Names Epidermal growth factor receptor kinase substrate 8 like protein 2 antibody; Epidermal growth factor receptor kinase substrate 8-like protein 2 antibody; Epidermal growth factor receptor pathway substrate 8 like protein 2 antibody; Epidermal growth factor receptor pathway substrate 8 related protein 2 antibody; Epidermal growth factor receptor pathway substrate 8-related protein 2 antibody; EPS8 like 2 antibody; EPS8 like protein 2 antibody; EPS8 related protein 2 antibody; EPS8-like protein 2 antibody; EPS8-related protein 2 antibody; EPS8L 2 antibody; EPS8L2 antibody; EPS8R 2 antibody; EPS8R2 antibody; ES8L2_HUMAN antibody; FLJ16738 antibody; FLJ21935 antibody; FLJ22171 antibody; MGC126530 antibody; MGC3088 antibody
Raised in Rabbit
Species Reactivity Human,Mouse
Immunogen Synthesized peptide derived from the N-terminal region of Human Eps8L2.
Conjugate Non-conjugated
Isotype IgG
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form Liquid
Tested Applications WB, IHC, IF, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:40000
Protocols Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Data

Function Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. In the cochlea, is required for stereocilia maintenance in adult hair cells (By similarity).
Gene References into Functions
  1. frame-shift variant (c.1014delC; p.Ser339Alafs*15) was identified in EPS8L2, encoding Epidermal growth factor receptor Pathway Substrate 8 L2, a protein of hair cells' stereocilia previously implicated in progressive deafness in the mouse PMID: 26282398
Involvement in disease Deafness, autosomal recessive, 106 (DFNB106)
Subcellular Location Cytoplasm, Cell projection, stereocilium
Protein Families EPS8 family
Tissue Specificity Detected in fibroblasts and placenta.
Database Links

HGNC: 21296

OMIM: 614988

KEGG: hsa:64787

STRING: 9606.ENSP00000320828

UniGene: Hs.55016

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