EXOC3 Antibody, FITC conjugated

Datasheet

Code	CSB-PA527663LC01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) EXOC3 Polyclonal antibody

Uniprot No.

O60645

Target Names

EXOC3

Alternative Names

EXOC 3 antibody; Exoc3 antibody; EXOC3_HUMAN antibody; Exocyst complex component 3 antibody; Exocyst complex component Sec 6 antibody; Exocyst complex component Sec6 antibody; rSec 6 antibody; Sec 6 antibody; Sec 6 homolog antibody; Sec 6p antibody; Sec6 antibody; SEC6 L1 antibody; SEC6 like 1 antibody; Sec6 protein antibody; SEC6L1 antibody; Sec6p antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Exocyst complex component 3 protein (410-756AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

FITC

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Antigen Affinity purified & Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

Gene References into Functions

Sec6 regulate Bcl-2 and Mcl-1 expressions but not Bcl-xl in malignant peripheral nerve sheath tumor cells. PMID: 26892009
Sec6 regulates NF-kappaB transcriptional activity via the control of the phosphorylation of IkappaBalpha, p90RSK1, and ERK PMID: 26247921
The study explores the role of the exocyst complex component Sec6/8 in genomic stability. PMID: 26283729
Sec6 regulates cytoplasmic translocation of p27 through p27 phosphorylation at Thr157, thereby promoting p27 degradation in the cytoplasm via interaction with Jab1 and Siah1 and suppressing cell cycle progression. PMID: 24949832
Data demonstrate that the expression of alpha-E-catenin is increased by Sec6 siRNAs, and E-cadherin and beta-catenin localize mainly at the cell-cell contact region in HSC3 cells, which were transfected with Sec6 siRNA. PMID: 22381337

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Subcellular Location

Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone. Midbody. Golgi apparatus. Cell projection, neuron projection.

Protein Families

SEC6 family

Tissue Specificity

Expressed in epididymis (at protein level).

Database Links

HGNC: 30378

OMIM: 608186

KEGG: hsa:11336

STRING: 9606.ENSP00000323377

UniGene: Hs.481464

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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