Code | CSB-PA007936LA01HU |
Size | US$166 |
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The F9 Antibody (Product code: CSB-PA007936LA01HU) is Non-conjugated. For F9 Antibody with conjugates, please check the following table.
Application | Recommended Dilution |
---|---|
IHC | 1:20-1:200 |
IF | 1:50-1:200 |
Immunizing a rabbit with the recombinant human coagulation factor IX protein (144-239aa) is the first step for the F9 antibody preparation. The resulting F9 polyclonal antibody mixture is secondly isolated from the rabbit's serum and then purified through protein G affinity chromatography. Its purity is up to 95%. The purified F9 polyclonal antibody is tested for its specificity for human coagulation factor IX protein in ELISA, IHC, and IF assays.
Coagulation factor IX protein, also known as the Christmas factor, is a clotting factor that plays an important role in the blood coagulation cascade. The main function of factor IX is to activate the coagulation pathway by catalyzing the conversion of factor X to factor Xa. Factor Xa then participates in the conversion of prothrombin to thrombin, which leads to the formation of a blood clot. Factor IX deficiency leads to hemophilia B, a bleeding disorder characterized by a deficiency in clotting factor IX activity.
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