FABP7 Antibody

1. Normal sleep requires the astrocyte brain-type fatty acid binding protein FABP7. PMID: 28435883
2. BLBP was highly expressed in glioblastoma tissues.Increased BLBP expression in glioblastoma is associated with poor survival.BLBP mediates the proliferation of human glioblastoma cells by regulating ERK1/2 signaling pathway. PMID: 29288341
3. Data indicate that the levels of fatty acid binding protein 7 (FABP7) dramatically decreased during passage of the renal cell carcinomas (RCCs) cell line TUHR14TKB. PMID: 28292269
4. FABP7 is overexpressed in clear cell renal cell carcinoma and promotes cell growth by the activation of ERK and Stat3 signaling pathways PMID: 25192834
5. FABP7 and HMGCS2 may have roles in apocrine differentiation categorizing apocrine carcinoma of the breast PMID: 25389781
6. The mRNA/protein expressions of FABP7 was lower in the stenotic colon segment tissue than in the normal colon segment tissue of Hirschsrung disease patients. PMID: 24966941
7. These results suggest an important role of Rev-erbalpha and Fabp7 in adult neurogenesis. PMID: 24932636
8. identified 98 transposable element-FABP7 gene chimeric transcripts that were exclusively expressed in primary diffuse large B-cell lymphoma (DLBCL) cases and confirmed several in DLBCL-derived cell lines PMID: 25114248
9. FABP7 and FABP5 are differentially expressed in oligodendrocyte lineage cells and regulate their proliferation and/or differentiation. PMID: 24114376
10. Our data introduces FABP7 as a marker for glioma stem cells and further highlights its possible significance for glioma diagnosis and treatment. PMID: 24274717
11. Report feasibility of detecting B-FABP as biomarker for ischemic brain damage during extrcorporeal circulation in coronary artery bypass grafting patients. PMID: 23020859
12. FABP7 is almost exclusively expressed in neurospheres and not in the adherent cells, derived from the same glioblastoma tumor. PMID: 23284888
13. A fatty acid-binding protein 7/RXRbeta pathway enhances survival and proliferation in triple-negative breast cancer. PMID: 22322885
14. Considerable heterogeneity in expression patterns of FABP7 within breast cancer elates to differences in biological behaviour especially in basal-like breast cancer. PMID: 22562177
15. identified its binding target by proteomic analysis as fatty acid binding protein 7 (FABP7), also known as brain lipid binding protein) which is highly expressed in neural stem cells and localized in the cytoplasm PMID: 22689954
16. These data provide the first evidence of direct transactivation of the FABP7 proximal promoter by PAX6 and suggest a synergistic mechanism for PAX6 and other co-factor(s) in regulating FABP7 expression in malignant glioma. PMID: 22583899
17. Data show that three putative FABP7 promoter regions drive reporter gene expression in renal cell carcinoma cell lines, but not in the HEK293 cell line. PMID: 21771320
18. expression of BLBP in activated astrocytes negatively correlates with disease duration and in parallel with remyelination failure PMID: 21620951
19. BFABP is involved in cell proliferation and migration of human renal carcinoma cells. PMID: 21399875
20. High FABP7 is associated with malignant glioma. PMID: 20834042
21. We have identified a novel subgroup of basal phenotype (BP) class of breast cancers showing FABP7 expression that have significantly better clinical outcome. PMID: 19590950
22. this study is the first to demonstrate overexpression of FABP-7 in triple-negative breast cancers PMID: 19608352
23. FABP7 may function as a tumor progression gene in melanoma PMID: 19587692
24. overall structure exhibits the typical backbone conformation described for other members of the FABP family, consisting of antiparallel beta-strands that form two almost orthogonal beta-sheets, a helix-turn-helix motif and a short N-terminal helical loop PMID: 12479569
25. BLBP, stimulated by Ras-independent pathways, regulates Schwann cell-axon interactions in normal peripheral nerve and peripheral nerve tumors. PMID: 12612091
26. Overexpression of FABP7 in Down syndrome fetal brains. PMID: 12771203
27. data indicate that MRG is a mediator of the differentiating effects of pregnancy on breast epithelium PMID: 12975368
28. A possible mechanism for the association of nuclear FABP7 & poor prognosis of glioblastoma multiforme is that nuclear FABP7 may be induced by EGFR activation to promote migration of GBM tumor cells. PMID: 16623952
29. relation between FABP7, astrocytic features, invasion and poor prognosis and suggests that EGFR amplification is associated with nuclear translocation of FABP7. PMID: 17415524
30. There were not significant difference in B-FABP expression between ductal infiltrating carcinoma and benign tissue in human breast cancer. PMID: 17428383
31. Upregulation of FABP7 in renal cell carcinoma was confirmed by quantitative RT-PCR. PMID: 17646957
32. B-FABP expression in malignant glioma cells is accompanied by the appearance of radial glial-like properties, as well as reduced transformation. B-FABP depletion results in decreased migration, reduction in cell processes, & a more transformed phenotype. PMID: 17898869
33. Decreased expression of FABP-7 in fetal cystic adenomatoid malformation (CCAM) suggests FABP-7 may have a role in pulmonary development and in the pathogenesis of CCAM. PMID: 18391847
34. Both in vitro Reelin treatment and overexpression of Notch-1 intracellular domain induced BLBP expression and a radial glial phenotype in an immortalized human neural progenitor cell line, isolated from the cortex of 14 weeks old fetus PMID: 18593473
35. High expression of FABP7 is associated with melanoma PMID: 18826602
36. NFI family of transcription factors plays a key role in the regulation of both the B-FABP and GFAP genes in malignant glioma cells. PMID: 19540848
37. Increases tumor cell motility in vitro and over-expression is associated with poor prognosis in glioblastoma patients PMID: 15827123
38. Functional analysis in mice. PMID: 12975368

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HGNC: 3562

OMIM: 602965

KEGG: hsa:2173

STRING: 9606.ENSP00000357429

UniGene: Hs.26770