FADS1 Antibody, HRP conjugated

Datasheet
Code CSB-PA007959LB01HU
Size US$299
Uniprot No. O60427
Protocols ELISA Protocol
Immunogen Recombinant Human Fatty acid desaturase 1 protein (1-121AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Isoform 2 does not exhibit any catalytic activity toward 20:3n-6, but it may enhance FADS2 activity (By similarity). Isoform 1 is a component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3). Catalyzes the desaturation of dihomo-gamma-linoleic acid (DHGLA) (20:3n-6) and eicosatetraenoic acid (20:4n-3) to generate arachidonic acid (AA) (20:4n-6) and eicosapentaenoic acid (EPA)(20:5n-3), respectively.
Form Liquid
Conjugate HRP
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Fatty acid desaturase 1 (EC 1.14.19.-) (Delta(5) fatty acid desaturase) (D5D) (Delta(5) desaturase) (Delta-5 desaturase), FADS1, FADSD5
Immunogen Species Homo sapiens (Human)
Research Area Tags & Cell Markers
Target Names FADS1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Isoform 2 does not exhibit any catalytic activity toward 20
Subcellular Location Isoform 1: Endoplasmic reticulum membrane, Multi-pass membrane protein, Mitochondrion, SUBCELLULAR LOCATION: Isoform 2: Endoplasmic reticulum membrane, Multi-pass membrane protein
Protein Families Fatty acid desaturase type 1 family
Tissue Specificity Widely expressed, with highest levels in liver, brain, adrenal gland and heart. Highly expressed in fetal liver and brain.
Database Links

HGNC: 3574

OMIM: 606148

KEGG: hsa:3992

STRING: 9606.ENSP00000322229

UniGene: Hs.503546

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