FADS1 Antibody

Datasheet
Code CSB-PA978301
Size US$299
Uniprot No. O60427
Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA978301(FADS1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA978301(FADS1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
  • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal brain tissue, Primary antibody: CSB-PA978301(FADS1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunogen Fusion protein of Human FADS1
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Tested Applications ELISA,WB,IHC;ELISA:1:1000-1:2000,WB:1:200-1:1000,IHC:1:100-1:300
Relevance The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.
Form Liquid
Conjugate Non-conjugated
Storage Buffer -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method Antigen affinity purification
Isotype IgG
Alias fatty acid desaturase 1
Immunogen Species Homo sapiens (Human)
Target Names FADS1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Isoform 2 does not exhibit any catalytic activity toward 20
Subcellular Location Isoform 1: Endoplasmic reticulum membrane, Multi-pass membrane protein, Mitochondrion, SUBCELLULAR LOCATION: Isoform 2: Endoplasmic reticulum membrane, Multi-pass membrane protein
Protein Families Fatty acid desaturase type 1 family
Tissue Specificity Widely expressed, with highest levels in liver, brain, adrenal gland and heart. Highly expressed in fetal liver and brain.
Database Links

HGNC: 3574

OMIM: 606148

KEGG: hsa:3992

STRING: 9606.ENSP00000322229

UniGene: Hs.503546

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