FARP2 Antibody

Code CSB-PA977826
Size US$297
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  • Western blot analysis of extracts from HuvEc cells, using FIR antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) FARP2 Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
FARP2 antibody; FARP2_HUMAN antibody; FERM antibody; FERM domain including RhoGEF antibody; FERM; RhoGEF and pleckstrin domain protein 2 antibody; FERM; RhoGEF and pleckstrin domain-containing protein 2 antibody; FGD1 related Cdc42 GEF antibody; FIR antibody; FRG antibody; KIAA0793 antibody; PH domain-containing family C member 3 antibody; Pleckstrin homology domain-containing family C member 3 antibody; PLEKHC3 antibody; RhoGEF and pleckstrin domain protein 2 antibody; RhoGEF and pleckstrin domain-containing protein 2 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthesized peptide derived from Internal of Human FIR.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion.
Gene References into Functions
  1. FRG is a member of Cdc42-GEF and plays an important role in the signaling pathway downstream of G protein-coupled receptors PMID: 12771149
Database Links

HGNC: 16460

OMIM: 617586

KEGG: hsa:9855

STRING: 9606.ENSP00000264042

UniGene: Hs.726316

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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