FGFBP1 Antibody

1. These findings indicate that the miR-146a-CREB3L1-FGFBP1 signaling axis plays an important role in the regulation of angiogenesis in human umbilical vein endothelial cells. PMID: 27121396
2. Genetic polymorphism in the human FGFBP1 gene was associated with higher gene expression and an increased risk of familial Hypertension. PMID: 29158353
3. Up-regulated Sox12 induced by FoxQ1 promotes hepatocellular carcinoma invasion and metastasis by transactivating Twist1 and FGFBP1 expression. PMID: 25704764
4. overexpression of FGFBP1 or loss of WISP-2 expression is closely related to the metastasis, invasion and poor prognosis of gallbladder cancer. PMID: 23592278
5. FGFBP1 associates with hypertension and that systematic analysis of signaling pathways can identify previously undescribed genetic associations. PMID: 21436287
6. Sequence variation in FGFBP1 may contribute to variation in bone mineral density, possibly influencing osteoporosis risk. PMID: 20450993
7. Upregulation of FGF-BP expression after injury stimulates FGF activity at the wound site, thus enhancing the process of epithelial repair. PMID: 15806171
8. the FGF interaction domain is contained in the C terminus of FGF-BP1 PMID: 16257968
9. FGF-BP can be rate-limiting for tumor growth and serves as an angiogenic switch molecule, and that it represents an increasingly promising target molecule in anti-tumor therapy[review] PMID: 16324873
10. The upregulation of FGF-BP by regenerating renal tubular epithelial cells may provide a mechanism by which the regenerative and angiogenic activity of FGF-2 in renal capillaries can be modulated in children with HIV-HUS and other renal disease. PMID: 16352855
11. KLF5 promotes breast cell survival partially through fibroblast growth factor-binding protein 1-pERK-mediated dual specificity MKP-1 protein phosphorylation and stabilization. PMID: 19411256
12. KLF5 may promote breast cancer cell proliferation at least partially through directly activating the FGF-BP mRNA transcription. PMID: 19668233

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HGNC: 19695

OMIM: 607737

KEGG: hsa:9982

STRING: 9606.ENSP00000259988

UniGene: Hs.1690