FOXN4 Antibody

Code CSB-PA850403LA01HU
Size US$166
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Image
  • Immunofluorescence staining of HepG2 cells with CSB-PA850403LA01HU at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) FOXN4 Polyclonal antibody
Uniprot No.
Target Names
FOXN4
Alternative Names
FOXN4Forkhead box protein N4 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Forkhead box protein N4 protein (89-194AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The FOXN4 Antibody (Product code: CSB-PA850403LA01HU) is Non-conjugated. For FOXN4 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA850403LB01HU FOXN4 Antibody, HRP conjugated ELISA
FITC CSB-PA850403LC01HU FOXN4 Antibody, FITC conjugated
Biotin CSB-PA850403LD01HU FOXN4 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IF
Recommended Dilution
Application Recommended Dilution
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Transcription factor essential for neural and some non-neural tissues development, such as retina and lung respectively. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3'. During development of the central nervous system, is required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates through activating DLL4-NOTCH signaling. Also acts synergistically with ASCL1/MASH1 to activate DLL4-NOTCH signaling and drive commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the atrioventricular canal and is indirectly required for patterning the distal airway during lung development.
Subcellular Location
Nucleus.
Database Links

HGNC: 21399

OMIM: 609429

KEGG: hsa:121643

STRING: 9606.ENSP00000299162

UniGene: Hs.528316

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