GATAD2B Antibody

1. GATAD2B interacts with C-MYC to enhance KRAS driven tumor growth. PMID: 30013058
2. This data suggests that 1q21.3 microdeletion is a recurrent microdeletion syndrome with distinguishable phenotypes, and loss of function of GATAD2B is the major contributor of the characteristic facies and ID. PMID: 28211977
3. findings suggest that GATAD2B serves as an important mediator of progesterone-progesterone receptor suppression of proinflammatory and contractile genes during pregnancy; decreased GATAD2B expression near term may contribute to the decline in progesterone receptor function, leading to labor PMID: 28576827
4. This is the first report of GATAD2B in Chinese ID patients. Our findings will broaden the spectrum of GATAD2B mutations and facilitate genetic diagnosis and counseling. PMID: 28077840
5. p66beta might be important for the regulation of LOX in the nucleus. PMID: 25118846
6. Detailed clinical description showed that all four individuals with a GATAD2B aberration had a distinctive phenotype with childhood hypotonia, severe intellectual disability. PMID: 23644463
7. identification as potent transcriptional repressors interacting with MBD2 and MBD3 PMID: 12183469

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HGNC: 30778

OMIM: 614998

KEGG: hsa:57459

STRING: 9606.ENSP00000357644

UniGene: Hs.4779