GDF7 Antibody, Biotin conjugated

Code CSB-PA768769LD01HU
Size US$166
Order now
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) GDF7 Polyclonal antibody
Uniprot No.
Target Names
GDF7
Alternative Names
bmp12 antibody; bone morphogenetic protein 12 antibody; GDF-7 antibody; Gdf7 antibody; GDF7_HUMAN antibody; growth differentiation factor 7 antibody; Growth/differentiation factor 7 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Growth/differentiation factor 7 protein (322-450AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
May play an active role in the motor area of the primate neocortex.
Gene References into Functions
  1. BMP-12 activates tenogenic pathway in human adipose stem cells. PMID: 28214472
  2. The Barrett-associated variants at GDF7 and TBX5 also increase esophageal adenocarcinoma risk. PMID: 26783083
  3. closest protein-coding genes were respectively GDF7 (rs3072), which encodes a ligand in the bone morphogenetic protein pathway, and TBX5 (rs2701108), which encodes a transcription factor that regulates esophageal and cardiac development PMID: 25447851
  4. BMP12 induces tenogenic differentiation of adipose-derived stromal cells via the Smad1/5/8 pathway. PMID: 24155967
  5. studies show that even though tenogenic (BMP 12 and BMP 13) and osteogenic (BMP2) BMPs bind the same receptors with high affinity they signal much differently and result in differential activation of osteogenic and tenogenic markers PMID: 21702718
  6. induces ligamentogenic differentiation in mesenchymal progenitors PMID: 20334610
  7. stimulates expression of both chondrogenic and osteoblstic markers in pluripotent mesenchymal C3H10T1/2 cells. PMID: 20102312
  8. In mouse, the expression of Gdf7 in roof plate cells is required for the fidelity of commissural axon growth. PMID: 12741987

Show More

Hide All

Subcellular Location
Secreted.
Protein Families
TGF-beta family
Database Links

HGNC: 4222

OMIM: 604651

KEGG: hsa:151449

STRING: 9606.ENSP00000272224

UniGene: Hs.447688

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
webinars: DT3C facilitates antibody internalization X
Place an order now

I. Product details

*
*
*
*

II. Contact details

*
*

III. Ship To

*
*
*
*
*
*
*

IV. Bill To

*
*
*
*
*
*
*
*