GNB2 Antibody

Datasheet

Code	CSB-PA009604GA01HU
Size	$600
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

P62879

Target Names

GNB2

Alternative Names

G protein beta 2 subunit antibody; G protein subunit beta 2 antibody; G protein subunit beta-2 antibody; GBB2_HUMAN antibody; Gnb2 antibody; Gnb2l1 antibody; Guanine nucleotide binding protein beta 2 subunit antibody; Guanine nucleotide binding protein G I G S G T beta 2 subunit 2 antibody; Guanine nucleotide binding protein G protein beta polypeptide 2 antibody; Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 antibody; OTTHUMP00000174601 antibody; OTTHUMP00000174602 antibody; RACK1 antibody; Receptor for activated C kinase antibody; Receptor of activated protein kinase C 1 antibody; Signal transducing guanine nucleotide binding regulatory protein beta antibody; Transducin beta chain 2 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human GNB2

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB,IHC,IF

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

Gene References into Functions

A GNB2 gene mutation is associated with familial sinus node and atrioventricular conduction dysfunction. PMID: 28219978
MIF and GNbeta2 interacted with influenza A H1N1 virus PB1-F2 protein. PMID: 23043599
Results indicate that G protein beta2 (Gbeta2) is required for starvation-induced NF-kappaB activation and constitutive NF-kappaB activity. PMID: 22917497
We conclude that the Gbetagamma complex interacts with the GR and suppresses its transcriptional activity by associating with the transcriptional complex formed on GR-responsive promoters. PMID: 15955845
Recombinant Gbetagamma subunits were used to establish that the Gbeta(2)gamma(2) dimer can selectively reconstitute the inhibition of alpha(1H) channels in isolated membrane patches. PMID: 16973746

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Subcellular Location

Cytoplasm, perinuclear region.

Protein Families

WD repeat G protein beta family

Database Links

HGNC: 4398

OMIM: 139390

KEGG: hsa:2783

STRING: 9606.ENSP00000305260

UniGene: Hs.185172

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Service

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Chemokine signaling pathway PI3K-Akt signaling pathway Ras signaling pathway Apelin signaling pathway Glutamatergic synapse

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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