GNG12 Antibody

Datasheet
Code CSB-PA883362OA01HU
Size US$299
Uniprot No. Q9UBI6
Image
  • IHC image of CSB-PA883362OA01HU diluted at 1:100 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Immunogen Recombinant Human Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 protein (2-17AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA, IHC; Recommended dilution: IHC:1:20-1:200
Relevance Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Antigen Affinity Purified
Isotype IgG
Clonality Polyclonal
Alias Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12, GNG12
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Research Area Signal Transduction
Target Names GNG12
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
Subcellular Location Cell membrane, Lipid-anchor, Cytoplasmic side
Protein Families G protein gamma family
Database Links

HGNC: 19663

OMIM: 615405

KEGG: hsa:55970

STRING: 9606.ENSP00000360021

UniGene: Hs.431101

Pathway Chemokine signaling pathway
MAPK signaling pathway
PI3K-Akt signaling pathway
Regulation of actin cytoskeleton
Ras signaling pathway
Apelin signaling pathway
Glutamatergic synapse

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