GPC Antibody

Datasheet
Code CSB-PA357830LA01LKW
See More Details Free Antibody trial simple
Size US$299
Uniprot No. P09991
Protocols ELISA Protocol
Immunogen Recombinant Lymphocytic choriomeningitis virus Pre-glycoprotein polyprotein GP complex protein (266-498AA)
Raised in Rabbit
Species Reactivity Lymphocytic choriomeningitis virus
Tested Applications ELISA
Relevance Stable signal peptide (SSP) is cleaved but is apparently retained as the third component of the GP complex. The SSP is required for efficient glycoprotein expression, post-translational cleavage of GP1 and GP2, glycoprotein transport to the cell plasma membrane, formation of infectious virus particles, and acid pH-dependent glycoprotein-mediated cell fusion.
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Pre-glycoprotein polyprotein GP complex (Pre-GP-C) [Cleaved into: Stable signal peptide (SSP); Glycoprotein G1 (GP1); Glycoprotein G2 (GP2)], GPC, GP-C
Immunogen Species Lymphocytic choriomeningitis virus (strain Armstrong) (LCMV)
Research Area Others
Target Names GPC
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Stable signal peptide is cleaved but is apparently retained as the third component of the GP complex. The SSP is required for efficient glycoprotein expression, post-translational cleavage of GP1 and GP2, glycoprotein transport to the cell plasma membrane, formation of infectious virus particles, and acid pH-dependent glycoprotein-mediated cell fusion.
Subcellular Location Stable signal peptide: Virion membrane, Multi-pass membrane protein, Host cell membrane, Multi-pass membrane protein, SUBCELLULAR LOCATION: Glycoprotein G1: Virion membrane, Peripheral membrane protein, Host cell membrane, Peripheral membrane protein, SUBCELLULAR LOCATION: Glycoprotein G2: Virion membrane, Single-pass membrane protein, Host cell membrane, Single-pass membrane protein
Protein Families Arenaviridae GPC protein family
Database Links

KEGG: vg:956591

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