GPR179 Antibody

Datasheet

Code	CSB-PA757664LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA757664LA01HU at dilution of 1:100 Immunofluorescent analysis of Hela cells using CSB-PA757664LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) GPR179 Polyclonal antibody

Uniprot No.

Q6PRD1

Target Names

GPR179

Alternative Names

G protein coupled receptor 179 antibody; GP179_HUMAN antibody; GPR158 like 1 antibody; GPR158L1 antibody; GPR179 antibody; Probable G-protein coupled receptor 158-like 1 antibody; Probable G-protein coupled receptor 179 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Probable G-protein coupled receptor 179 protein (1440-1671AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The GPR179 Antibody (Product code: CSB-PA757664LA01HU) is Non-conjugated. For GPR179 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA757664LB01HU	GPR179 Antibody, HRP conjugated	ELISA
FITC	CSB-PA757664LC01HU	GPR179 Antibody, FITC conjugated
Biotin	CSB-PA757664LD01HU	GPR179 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Orphan receptor, involved in vision. Required for signal transduction through retinal depolarizing bipolar cells.

Gene References into Functions

In this study, a novel compound heterozygous mutation, c.[1A>G]; [608G>T] (p.[0?]; p.[W203L]), was identified in the LRIT3 gene of a proband. No mutations were identified in the CABP4 or GPR179 gene. PMID: 27428514
We found 1 mutation in GPR179 in congenital stationary night blindness. PMID: 23714322
Additional screening with Sanger sequencing of 40 patients identified three other cCSNB patients harboring additional allelic mutations in GPR179. PMID: 22325361

Involvement in disease

Night blindness, congenital stationary, 1E (CSNB1E)

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Families

G-protein coupled receptor 3 family

Tissue Specificity

Expressed in the retina.

Database Links

HGNC: 31371

OMIM: 614515

KEGG: hsa:440435

STRING: 9606.ENSP00000345060

UniGene: Hs.462915

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

G protein coupled receptor signaling pathway Target Therapy

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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