GPR179 Antibody, HRP conjugated

Code CSB-PA757664LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) GPR179 Polyclonal antibody
Uniprot No.
Target Names
GPR179
Alternative Names
G protein coupled receptor 179 antibody; GP179_HUMAN antibody; GPR158 like 1 antibody; GPR158L1 antibody; GPR179 antibody; Probable G-protein coupled receptor 158-like 1 antibody; Probable G-protein coupled receptor 179 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Probable G-protein coupled receptor 179 protein (1440-1671AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Orphan receptor, involved in vision. Required for signal transduction through retinal depolarizing bipolar cells.
Gene References into Functions
  1. In this study, a novel compound heterozygous mutation, c.[1A>G]; [608G>T] (p.[0?]; p.[W203L]), was identified in the LRIT3 gene of a proband. No mutations were identified in the CABP4 or GPR179 gene. PMID: 27428514
  2. We found 1 mutation in GPR179 in congenital stationary night blindness. PMID: 23714322
  3. Additional screening with Sanger sequencing of 40 patients identified three other cCSNB patients harboring additional allelic mutations in GPR179. PMID: 22325361
Involvement in disease
Night blindness, congenital stationary, 1E (CSNB1E)
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
G-protein coupled receptor 3 family
Tissue Specificity
Expressed in the retina.
Database Links

HGNC: 31371

OMIM: 614515

KEGG: hsa:440435

STRING: 9606.ENSP00000345060

UniGene: Hs.462915

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