GRHPR Antibody

Datasheet

Code	CSB-PA009897HA01HU
Size	US$166
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Image	Western Blot Positive WB detected in: Rat liver tissue, Mouse liver tissue All lanes: GRHPR antibody at 3.5μg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 36, 28 kDa Observed band size: 36 kDa Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA009897HA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA009897HA01HU at dilution of 1:100 Immunofluorescent analysis of HepG2 cells using CSB-PA009897HA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) GRHPR Polyclonal antibody

Uniprot No.

Q9UBQ7

Target Names

GRHPR

Alternative Names

GLXR antibody; glycerate 2 dehydrogenase antibody; GLYD antibody; Glyoxylate reductase/hydroxypyruvate reductase antibody; Grhpr antibody; GRHPR_HUMAN antibody; OTTHUMP00000021379 antibody; OTTHUMP00000021380 antibody; OTTHUMP00000046131 antibody; PH 2 antibody; PH2 antibody; Primary hyperoxaluria type 2 antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Human Glyoxylate reductase/hydroxypyruvate reductase protein (1-328AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The GRHPR Antibody (Product code: CSB-PA009897HA01HU) is Non-conjugated. For GRHPR Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA009897HB01HU	GRHPR Antibody, HRP conjugated	ELISA
FITC	CSB-PA009897HC01HU	GRHPR Antibody, FITC conjugated
Biotin	CSB-PA009897HD01HU	GRHPR Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC, IF

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities. Reduces hydroxypyruvate to D-glycerate, glyoxylate to glycolate oxidizes D-glycerate to hydroxypyruvate.

Gene References into Functions

GRHPR was genotyped in Japanese patients with PH2 and all GRHPR mutations described to date were reviewed in terms of geographic and ethnic association PMID: 24116921
Our findings suggest that the GRHPR defect in noncancerous tissues may represent an independent predictor of poor survival for hepatocellular carcinoma patients after curative resection PMID: 23486161
GRHPR directly interacts with SVCT1. PMID: 23599041
substrate specificity of human glyoxylate reductase PMID: 16756993
the GRHPR gene may have a role in primary hyperoxaluria type 2 in a Japanese patient [case report] PMID: 17510093

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Involvement in disease

Hyperoxaluria primary 2 (HP2)

Protein Families

D-isomer specific 2-hydroxyacid dehydrogenase family

Tissue Specificity

Ubiquitous. Most abundantly expressed in the liver.

Database Links

HGNC: 4570

OMIM: 260000

KEGG: hsa:9380

STRING: 9606.ENSP00000313432

UniGene: Hs.155742

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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