GRHPR Antibody, HRP conjugated

Datasheet

Code	CSB-PA009897HB01HU
Size	US$166
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) GRHPR Polyclonal antibody

Uniprot No.

Q9UBQ7

Target Names

GRHPR

Alternative Names

GLXR antibody; glycerate 2 dehydrogenase antibody; GLYD antibody; Glyoxylate reductase/hydroxypyruvate reductase antibody; Grhpr antibody; GRHPR_HUMAN antibody; OTTHUMP00000021379 antibody; OTTHUMP00000021380 antibody; OTTHUMP00000046131 antibody; PH 2 antibody; PH2 antibody; Primary hyperoxaluria type 2 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Glyoxylate reductase/hydroxypyruvate reductase protein (1-328AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

HRP

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities. Reduces hydroxypyruvate to D-glycerate, glyoxylate to glycolate oxidizes D-glycerate to hydroxypyruvate.

Gene References into Functions

GRHPR was genotyped in Japanese patients with PH2 and all GRHPR mutations described to date were reviewed in terms of geographic and ethnic association PMID: 24116921
Our findings suggest that the GRHPR defect in noncancerous tissues may represent an independent predictor of poor survival for hepatocellular carcinoma patients after curative resection PMID: 23486161
GRHPR directly interacts with SVCT1. PMID: 23599041
substrate specificity of human glyoxylate reductase PMID: 16756993
the GRHPR gene may have a role in primary hyperoxaluria type 2 in a Japanese patient [case report] PMID: 17510093

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Involvement in disease

Hyperoxaluria primary 2 (HP2)

Protein Families

D-isomer specific 2-hydroxyacid dehydrogenase family

Tissue Specificity

Ubiquitous. Most abundantly expressed in the liver.

Database Links

HGNC: 4570

OMIM: 260000

KEGG: hsa:9380

STRING: 9606.ENSP00000313432

UniGene: Hs.155742

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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