GSTA3 Antibody

Datasheet

Code	CSB-PA593946
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA593946(GSTA3 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA593946(GSTA3 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200) Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Human testis tissue, Primary antibody: CSB-PA593946(GSTA3 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
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Product Details
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Target Background

Product Details

Uniprot No.

Q16772

Target Names

GSTA3

Alternative Names

Glutathione S alkyltransferase A3 antibody; Glutathione S aralkyltransferase A3 antibody; Glutathione S aryltransferase A3 antibody; Glutathione S transferase A3 3 antibody; Glutathione S transferase A3 antibody; glutathione S transferase A3 subunit antibody; Glutathione S transferase alpha 3 antibody; Glutathione S transferase alpha type (Ya) antibody; glutathione S transferase Yc 1 antibody; glutathione S transferase Yc1 subunit antibody; Glutathione S-transferase A3 antibody; Glutathione S-transferase A3-3 antibody; Glutathione S-transferase Ya3 antibody; Glutathione S-transferase Yc antibody; glutathione transferase A3 subunit antibody; Glutathione transferase alpha 3 antibody; GST 2 2 antibody; GST AA antibody; GST class alpha antibody; GST class alpha member 3 antibody; GST class-alpha member 3 antibody; GST Yc1 antibody; GSTA 3 antibody; GSTA3 3 antibody; Gsta3 antibody; GSTA3-3 antibody; GSTA3_HUMAN antibody; Gstyc antibody; GTA 3 antibody; GTA3 antibody; MGC22232 antibody; S (hydroxyalkyl)glutathione lyase A3 antibody; Yc1 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Fusion protein of Human GSTA3

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,WB,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:2000-1:5000
WB	1:500-1:2000
IHC	1:25-1:100

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Catalyzes isomerization reactions that contribute to the biosynthesis of steroid hormones. Efficiently catalyze obligatory double-bond isomerizations of delta(5)-androstene-3,17-dione and delta(5)-pregnene-3,20-dione, precursors to testosterone and progesterone, respectively. Has substantial activity toward aflatoxin B1-8,9-epoxide.

Gene References into Functions

GSTA3 expression is significantly downregulated in human masticatory mucosa during wound healing PMID: 28005267
Density functional theory calculations used to propose a refined mechanism for the isomerization of delta(5)-androstene-3,17-dione catalyzed by GST A3-3 PMID: 24739064
analysis of how isomerization of the steroid Delta(5)-androstene-3,17-dione by the glutathione transferase A3-3 PMID: 25248748
describe an I71L polymorphism in GSTA3 that occurs at a low frequency in African populations PMID: 15454730
Analysis of the active centers of hGSTA3-3 reveals that residues in positions 12 and 208 may contribute to its disparate isomerase activity toward Delta(5)-AD. PMID: 15595823
Significantly contributes to the double-bond isomerization necessary for steroid hormone biosynthesis in complex systems, thereby complementing the indispensable 3beta-hydroxysteroid oxidoreductase activity of 3beta-hydroxysteroid dehydrogenase. PMID: 18426392

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Subcellular Location

Cytoplasm.

Protein Families

GST superfamily, Alpha family

Database Links

HGNC: 4628

OMIM: 605449

KEGG: hsa:2940

STRING: 9606.ENSP00000211122

UniGene: Hs.102484

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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