H2AFB1 Antibody

Datasheet

Code	CSB-PA010091LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA010091LA01HU at dilution of 1:100 Immunofluorescent analysis of MCF-7 cells using CSB-PA010091LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) H2AFB1 Polyclonal antibody

Uniprot No.

P0C5Y9

Target Names

H2AFB1

Alternative Names

H2AB1 antibody; H2AFB1 antibody; Histone H2A-Bbd type 1 antibody; H2A Barr body-deficient antibody; H2A.B antibody; H2A.Bbd antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Histone H2A-Bbd type 1 protein (1-115AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The H2AFB1 Antibody (Product code: CSB-PA010091LA01HU) is Non-conjugated. For H2AFB1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA010091LB01HU	H2AFB1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA010091LC01HU	H2AFB1 Antibody, FITC conjugated
Biotin	CSB-PA010091LD01HU	H2AFB1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Atypical histone H2A which can replace conventional H2A in some nucleosomes and is associated with active transcription and mRNA processing. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Nucleosomes containing this histone are less rigid and organize less DNA than canonical nucleosomes in vivo. They are enriched in actively transcribed genes and associate with the elongating form of RNA polymerase. They associate with spliceosome components and are required for mRNA splicing.

Subcellular Location

Nucleus. Chromosome.

Protein Families

Histone H2A family

Tissue Specificity

Present in mature sperm.

Database Links

HGNC: 22516

OMIM: 300445

KEGG: hsa:474382

STRING: 9606.ENSP00000346450

UniGene: Hs.534498

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What Are Histones: Unraveling Their Critical Roles in Disease Pathogenesis Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Necroptosis

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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