HIPK4 Antibody

Code CSB-PA072130
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using CSB-PA072130(HIPK4 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA072130(HIPK4 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
HIPK4
Alternative Names
HIPK 4 antibody; HIPK4 antibody; HIPK4_HUMAN antibody; Homeodomain interacting protein kinase 4 antibody; Homeodomain-interacting protein kinase 4 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Fusion protein of Human HIPK4
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:5000
IHC 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Protein kinase that phosphorylates human TP53 at Ser-9, and thus induces TP53 repression of BIRC5 promoter. May act as a corepressor of transcription factors (Potential).
Gene References into Functions
  1. loss of HIPK4 expression improves early skin epithelial differentiation accompanied by an increase in K8 and K18 expression, and improves late keratinocyte differentiation with an increase of epidermal identity PMID: 28966120
  2. Analysis of these mutants revealed that HIPK1, HIPK2 and HIPK3 but not HIPK4 are capable of autophosphorylating on other tyrosines PMID: 25630557
  3. homeodomain interacting protein kinase 4 could phosphorylate human p53 protein at serine 9, both in vitro and in vivo PMID: 18022393
Subcellular Location
Cytoplasm.
Protein Families
Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily
Database Links

HGNC: 19007

OMIM: 611712

KEGG: hsa:147746

STRING: 9606.ENSP00000291823

UniGene: Hs.79363

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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